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Tau Mouse Monoclonal Antibody (10E3)

Mouse Anti-Tau Mouse Monoclonal Antibody (10E3)

Product Specifications

Background

MAPT (microtubule associated protein tau) encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

CAS Number

9007-83-4

Product Name Alternative

MAPT

Gene ID

4137

Accession Number

P10636

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic Peptide of Tau

Clonality

Monoclonal

Tag

MAPT

Applications

WB, IHC, IF

Purification Method

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Molecular Weight

50-85kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Tau protein detects endogenous levels of MAPT.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:1000-2000; IHC 1:100-200; IF 1:50-200

Other Product Names

MAPT

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Mouse

Accession Number URL

http://www.uniprot.org/uniprot/P10636

Isotype

Mouse IgG1

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