Anti-Leptin Receptor Antibody [JA73-01]

Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

CD 295 antibody CD295 antibody CD295 antigen antibody Db antibody Fa antibody HuB219 antibody LEP R antibody LEP-R antibody LEPR antibody LEPR_HUMAN antibody LEPRD antibody Leptin receptor antibody Leptin receptor fatty antibody Leptin receptor gene related protein antibody Leptin receptor precursor antibody Leptin receptor precursor antibody OB R gene related protein antibody OB receptor antibody OB-R antibody OB-RGRP antibody obl antibody Obr antibody

Abbreviation

LEP-R, OB-R, LEPR, DB, OBR

Swiss Prot

P48357 Human; P48356 Mouse; Q62959 Rat

Cellular Locus

Cell membrane, Basolateral cell membrane.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human Leptin Receptor aa 1041-1090 / 1165.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

Mouse lung tissue lysate, mouse liver tissue lysate, K-562 cell lysates, HeLa cell lysates, rat brain tissue lysates, MCF-7, rat heart tissue, human liver carcinoma tissue, human prostate tissue, human kidney tissue, mouse small intestine tissue, K562.