Anti-Syndecan 1 Antibody [JM11-21]
Syndecan-1 (SYND1), also designated CD138, is a type I integral membrane proteoglycan that contains both chondroitin sulfate and heparan sulfate groups. It is expressed in mouse on pre-B cells, immature B cells and plasma cells. Syndecan-1 is also found on the basolateral surfaces of epithelial cells, endothelial cells of sprouting capillaries and embryonic condensing mesenchymal cells. Syndecan-1 functions as an extracellular matrix receptor which binds to collagens, Fibronectin and Thrombospondin. It has been shown to co-localize with Actin-rich filaments and may act to link the cytoskeleton to the extracellular matrix.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
SYND1, SDC1
Swiss Prot
P18827 Human; P18828 Mouse; P26260 Rat
Cellular Locus
Membrane, Secreted.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within Human Syndecan 1 aa 13-274 / 310.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 32 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
True
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