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Anti-CD147 Antibody [JF1-045]

Extracellular matrix metalloproteinase inducer (EMMPRIN), also designated basigin or CD147, is involved in the regulation of matrix remodeling at the epidermal-dermal interface. EMMPRIN stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

5A11 antigen antibody 5F7 antibody BASI_HUMAN antibody Basigin (Ok blood group) antibody Basigin antibody Blood brain barrier HT7 antigen antibody Bsg antibody CD 147 antibody CD147 antibody CD147 antigen antibody Collagenase stimulatory factor antibody EMMPRIN antibody Extracellular matrix metalloproteinase inducer antibody Leukocyte activation antigen M6 antibody M 6 antibody M6 antibody M6 leukocyte activation antigen antibody Neurothelin antibody OK antibody OK blood group antibody OK blood group antigen antibody TCSF antibody Tumor cell derived collagenase stimulatory factor antibody Tumor cell-derived collagenase stimulatory factor antibody

Abbreviation

EMMPRIN, TCSF, BSG

Swiss Prot

P35613 Human; P18572 Mouse; P26453 Rat

Cellular Locus

Cell membrane, Melanosome.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human CD147 aa 171-204 / 385.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P

Positive Control

HepG2 cell lysate, NCI-H226 cell lysate, 786-0 cell lysate, RAW264.7 cell lysate, mouse liver tissue lysate, rat liver tissue lysate, Hela, A431, SKOV-3, human colon carcinoma tissue, mouse brain tissue, mouse heart tissue, rat brain tissue, mouse testis tissue.

Concentration

1 mg/mL

Dilution

WB: 1:5,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 42 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

True

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