Anti-NeuN Antibody [SR45-07]

Neuronal nuclei (NeuN, Fox-3, RBFOX3) is a nuclear protein expressed in most post-mitotic neurons of the central and peripheral nervous systems. NeuN is not detected in Purkinje cells, sympathetic ganglion cells, Cajal-Retzius cells, INL retinal cells, inferior olivary, and dentate nucleus neurons. This neuronal protein was originally identified by immunoreactivity with a monoclonal antibody also called NeuN. Using MS-analysis, NeuN was later identified as the Fox-3 gene product. Fox-3 contains an RNA recognition motif and functions as a splicing regulator. Fox-3 regulates alternative splicing of NumB, promoting neuronal differentiation during development.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

FLJ56884 antibody FLJ58356 antibody Fox-1 homolog C antibody fox1 homolog C antibody Fox3 antibody FOX3NeuN antibody hexaribonucleotide binding protein 3 antibody HRNBP3 antibody NEUN antibody neuronal nuclei antibody Rbfox3 antibody RFOX3_HUMAN antibody RNA binding protein fox-1 homolog 3 antibody RNA binding protein, fox 1 homolog (C. elegans) 3 antibody hide

Abbreviation

RBFOX3

Swiss Prot

A6NFN3 Human; Q8BIF2 Mouse

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within human NeuN aa 20-60.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC, IHC-Fr

Positive Control

Mouse brain tissue lysate, rat brain tissue lysate, mouse cerebellum tissue lysate, rat cerebellum tissue lysate, SH-SY5Y cell lysate, SHG-44 cell lysate, rat cerebellum tissue, SHG-44, mouse cerebral cortex tissue, mouse cerebellum tissue, rat cerebral cortex tissue, mouse hippocampus tissue, rat hippocampus tissue, human brain tissue, SH-SY5Y, mouse brain tissue.