Tyrosinase Rabbit Polyclonal Antibody
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
TYR
Swiss Prot
P14679 Human
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide within Human Tyrosinase aa 51-100 / 529.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
B16F1, Hela, human urethral melanoma tissue, A431.
Concentration
1 mg/mL
Dilution
WB: 1:200-1:500 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC:1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
70 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
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