NSUN4 Rabbit Polyclonal Antibody
Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
NSUN4
Swiss Prot
Q96CB9 Human, Q9CZ57 Mouse
Cellular Locus
Mitochondrion.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Recombinant protein within N-terminal human NSUN4.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
MCF-7, 293, A549, HepG2, human liver cancer tissue, human kidney tissue, mouse testis tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 43 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
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