BMP11 Rabbit Polyclonal Antibody
GDF-11, a member of the Transforming Growth Factor (TGF) Beta superfamily, controls anterior/posterior patterning of the axial skeleton, regulates organogenesis by controlling expression of Gdnf, contributes to the control of Hox gene expression, and induces phosphorylation of Smad2. In addition, GDF-11 mediates signaling of Nodal during left-right patterning and development of head structures and inhibits generation of new neurons by neuronal progenitors in the olfactory epithelium.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
GDF-11,BMP-11
Swiss Prot
O95390 Human, Q9Z1W4 Mouse, Q9Z217 Rat
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within Human BMP11 aa 200-407.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Hela, SW480, HepG2, human colon cancer tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100;WB: 1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 45 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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