NSE Rabbit Polyclonal Antibody
Gamma-enolase is one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. Detection of NSE with antibodies can be used to identify neuronal cells and cells with neuroendocrine differentiation. NSE is produced by small cell carcinomas which are neuroendocrine in origin. NSE is therefore a useful tumor marker for lung cancer patients.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Swiss Prot
P09104 Human
Cellular Locus
Cytoplasm, cell membrane
Host
Rabbit
Species Reactivity
Human,Mouse,Rat,Zebrafish,Crucian-Carp
Immunogen
Synthetic peptide within N-terminal human NSE.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell
Positive Control
Hela, NIH/3T3, F9, human brain, mouse brain, A172, SHG-44, N2A hybrid fish (crucian-carp) brain tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:2000-1:5,000 ;IF-Cell: 1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
47 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
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