TRAF6 Rabbit Polyclonal Antibody
TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/TRANCE/RANKL and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Swiss Prot
Q9Y4K3 Human, P70196 Mouse, B5DF45 Rat
Cellular Locus
Cytoplasm, nucleus
Host
Rabbit
Species Reactivity
Human,Mouse,Rat,Chicken,Zebrafish
Immunogen
Synthetic peptide within C-terminal human TRAF6.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
IF-Cell, IHC-P, WB
Positive Control
Hela, MCF-7, F9, PC12, hybrid fish (crucian-carp) heart tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IF-Cell: 1:100-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 60 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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