Bag1 Rabbit Polyclonal Antibody
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of alternative translation initiation sites, including a non-AUG site. BAG gene has been implicated in age related neurodegenerative diseases as Alzheimer's. It has been demonstrated that BAG1 and BAG 3 regulate the proteasomal and lysosomal protein elimination pathways, respectively.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
BAG-1
Swiss Prot
Q99933 Human
Cellular Locus
Cytoplasm. Nucleus
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human Bag1 full sequence.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell
Positive Control
Hela, SW480, F9, HCT116, HT-29, HepG2, 293, 293T, A431
Concentration
1 mg/mL
Dilution
WB: 1:1000;IF-Cell: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
35, 38 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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