CREB1 Rabbit Polyclonal Antibody
CAMP responsive element binding protein 1, also known as CREB-1, is a protein that in humans is encoded by the CREB1 gene.This protein binds the cAMP response element, a DNA nucleotide sequence present in many viral and cellular promoters. The binding of CREB1 stimulates transcription.This protein is a CREB transcription factor that is a member of the leucine zipper family of DNA-binding proteins.CREB1 is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
CREB-1,cAMP-responsive element-binding protein 1
Swiss Prot
P16220 Human
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within N-terminal human CREB1.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
A431 cell lysate, PC12 cell lysate, Hela, human brain, mouse brain
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IF-Cell:1:200-1:500 ;IHC-P: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 35 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
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