SUZ12 Rabbit Polyclonal Antibody
Polycomb protein SUZ12 is a nuclear protein belonging to the VEFS (VRN2-EMF2-FIS2-SUZ12) family. It is overexpressed in breast and colon cancer, expressed at low levels in quiescent cells. Expression rises at the G1/S phase transition. A chromosomal aberration involving SUZ12 may be a cause of endometrial stromal tumors. The translocation generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
ChET 9 protein
Swiss Prot
Q15022 Human, Q80U70 Mouse
Cellular Locus
Nucleus
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide within Human SUZ12 aa 481-520 / 739.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB
Positive Control
MCF-7, Hela, SW480, 293T, N2A F9
Concentration
1 mg/mL
Dilution
WB: 1:2,000-1:5,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 83kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
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