NANOG Rabbit Polyclonal Antibody
NANOG is a transcription factor critically involved with self-renewal of undifferentiated embryonic stem cells. NANOG is thought to function in concert with other factors such as POU5F1 and SOX2 to establish ESC identity. Overexpression of NANOG in mouse embryonic stem cells causes them to self-renew in the absence of Leukemia inhibitory factor. NANOG overexpression in human embryonic stem cells enables their propagation for multiple passages during which the cells remain pluripotent.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
hNanog
Swiss Prot
Q9H9S0 Human, Q80Z64 Mouse
Cellular Locus
Nucleus
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide within mouse NANOG aa 56-100.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB
Positive Control
NCCIT cell lysate, JAR cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:2,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 35 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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