FOXD3 Rabbit Polyclonal Antibody
Forkhead box protein D3 (FOXD3) acts as a transcriptional repressor and binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3'. It promotes development of neural crest cells from neural tube progenitors and restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. FOXD3 is expressed in premigratory and migrating neural crest cells in the early embryo and in motorneuron and interneuron progenitors in the developing spinal cord. A variety of growth factors induce FoxD3 expression, including FGF8 and SNAIL, maintaining the effected cells in an undifferentiated state.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
HFH-2
Swiss Prot
Q9UJU5 Human, Q61060 Mouse
Cellular Locus
Nucleus
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to of Mouse FOXD3 aa 1-50 / 465.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB
Positive Control
NCCIT
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 48 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Bcl-2 (Apoptosis & Follicular Lymphoma Marker) (BCL2/2210R), CF568 conjugate, 0.1mg/mL
