Oct4 Rabbit Polyclonal Antibody
Oct-4 (POU5F1) is a transcription factor expressed in the totipotent and pluripotent stem cells of the pregastrulation embryo. It is also expressed in primordial germ cells and in the female germ line. OCT4 binds to the octamer motif (5'-ATTTGCAT-3') and forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. It is critical for early embryogenesis and for embryonic stem cell pluripotency.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
Oct-3,Oct-4,OTF-3
Swiss Prot
Q01860 Human, P20263 Mouse
Cellular Locus
Nucleus, Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide within human OCT-4 aa 269-309.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB
Positive Control
NCCIT, F9
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 39kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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