CD14 Rabbit Polyclonal Antibody
CD14 is a glycophosphatidylinositol-anchored protein expressed on the surfaces of monocytes and plymorphonuclear leukocytes. It cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). CD14 acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and up-regulates cell surface molecules, including adhesion molecules.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
CD14
Swiss Prot
P08571 Human, P10810 Mouse
Cellular Locus
Cell membrane, Golgi apparatus , Secreted.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide within human CD14 aa 154-196.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, FC
Positive Control
K562, SW480, Raji
Concentration
1 mg/mL
Dilution
WB: 1:1,000;IF-Cell: 1:50;FC: 1:50
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 40kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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