PCNA Mouse Monoclonal Antibody [4-E11]
Proliferating cell nuclear antigen (PCNA) is a member of the DNA sliding clamp family of proteins that assist in DNA replication. Crystal structure data suggests that a PCNA homotrimer ring can encircle and slide along the DNA double helix. Multiple proteins involved in DNA replication, DNA repair, and cell cycle control bind to PCNA rather than directly associating with DNA, thus facilitating fast processing of DNA. PCNA protein expression is a well-accepted marker of proliferation.
Product Specifications
Product Name Alternative
Abbreviation
PCNA
Swiss Prot
P12004 Human
Cellular Locus
Nucleus
Host
Mouse
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human PCNA aa 31-80 / 261.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB
Positive Control
Raji
Concentration
2 mg/mL
Dilution
WB: 1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
~30kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
CAS Number
9007-83-4
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