Cdk2 Mouse Monoclonal Antibody [10-D7]
Cyclin-dependent kinase 2 (p33CDK2) is an important component of the cell cycle machinery. It acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. Inhibition of CDK2-cyclin complexes can also be attributed to association with p27 Kip1 and p21 Waf1/Cip1.
Product Specifications
Product Name Alternative
Abbreviation
CDK2
Swiss Prot
P24941 Human
Cellular Locus
Cytoplasm, nucleus
Host
Mouse
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human Cdk2 aa 249-298 / 298.
Isotype
IgG2b
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
A549, F9, PC12, NCCIT
Concentration
2 mg/mL
Dilution
WB: 1:2000 ;IF-Cell: 1:500
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 34 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
CAS Number
9007-83-4
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