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Axl Mouse Monoclonal Antibody [C4-A8]

Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. AXL receptor tyrosine kinase has been shown to interact with TENC1.Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Adhesion related kinase antibody AI323647 antibody Ark antibody Axl antibody AXL oncogene antibody AXL receptor tyrosine kinase antibody AXL transforming gene antibody AXL transforming sequence/gene antibody EC 2.7.10.1 antibody JTK11 antibody Oncogene AXL antibody Tyro7 antibody Tyrosine protein kinase receptor UFO antibody Tyrosine-protein kinase receptor UFO antibody UFO antibody UFO_HUMAN antibody

Abbreviation

AXL

Swiss Prot

P30530 Human

Cellular Locus

Cell membrane.

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant protein with Human UFO aa 10-160 / 894.

Isotype

IgG1

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IF-Cell

Positive Control

Recombinant protein lysate, SW480, LOVO.

Concentration

2 mg/mL

Dilution

WB: 1:500 ;IF-Cell: 1:200-1:500

Purity

Protein G affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 98 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

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