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IL-31 Mouse Monoclonal Antibody [B7-B0]

Interleukin 31 (IL-31) is a secreted, T-cell-derived, short-chain member of the alpha-helical family of cytokines. The mature region is 141 amino acids (aa) in length and exhibits four alpha-helices. Human and mouse IL-31 are highly divergent at 24% aa sequence identity. The receptor for IL-31 is found on keratinocytes and monocytes. It is a heterodimer composed of the Oncostatin M receptor and a novel gp130-related molecule. IL-31 may be involved in pruritis, or skin itching.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

IL 31 antibody IL-31 antibody IL31 antibody IL31_HUMAN antibody Interleukin 31 antibody Interleukin-31 antibody

Abbreviation

IL-31

Swiss Prot

Q6EBC2 Human

Cellular Locus

Secreted.

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant protein within Human Interleukin 31 aa 1-164 / 164.

Isotype

IgG2a

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, ELISA

Positive Control

Bioactive recombinant human IL-31 protein.

Concentration

2 mg/mL

Dilution

WB: 1:2,000 ;ELISA: 1:5,000-1:10,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 18 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

No

Frequently Asked Questions

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