IL-31 Mouse Monoclonal Antibody [B7-B0]
Interleukin 31 (IL-31) is a secreted, T-cell-derived, short-chain member of the alpha-helical family of cytokines. The mature region is 141 amino acids (aa) in length and exhibits four alpha-helices. Human and mouse IL-31 are highly divergent at 24% aa sequence identity. The receptor for IL-31 is found on keratinocytes and monocytes. It is a heterodimer composed of the Oncostatin M receptor and a novel gp130-related molecule. IL-31 may be involved in pruritis, or skin itching.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
IL 31 antibody IL-31 antibody IL31 antibody IL31_HUMAN antibody Interleukin 31 antibody Interleukin-31 antibody
Abbreviation
IL-31
Swiss Prot
Q6EBC2 Human
Cellular Locus
Secreted.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within Human Interleukin 31 aa 1-164 / 164.
Isotype
IgG2a
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, ELISA
Positive Control
Bioactive recombinant human IL-31 protein.
Concentration
2 mg/mL
Dilution
WB: 1:2,000 ;ELISA: 1:5,000-1:10,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 18 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
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