CD11b Mouse Monoclonal Antibody [A2-9]
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
ITGAM
Swiss Prot
P11215 Human
Cellular Locus
Membrane.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within human CD11b 500-750 aa.
Isotype
IgG2b
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
TF-1 cell lysate, Jurkat cell lysate, human tonsil tissue, human spleen tissue, Raji.
Concentration
2 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:1,000 ;FC: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 127 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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