Bcl-2 Mouse Monoclonal Antibody [F7-1-A1]
Bcl-2 (B-cell lymphoma 2) is the founding member of the Bcl-2 family of apoptosis regulator proteins encoded by the BCL2 gene. It has been implicated in a number of cancers, including melanoma, breast, prostate, chronic lymphocytic leukemia, and lung carcinomas, as well as schizophrenia and autoimmunity. It is also thought to be involved in resistance to conventional cancer treatment.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
BCL2
Swiss Prot
P10415 Human, P10417 Mouse, P49950 Rat
Cellular Locus
Mitochondrion outer membrane, Nucleus membrane, Endoplasmic reticulum membrane, Cytoplasm.
Host
Mouse
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human BCL-2 aa 1-200.
Isotype
IgG2b
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Jurkat cell lysate, rat spleen tissue lysate, HepG2, human breast carcinoma tissue, mouse spleen tissue.
Concentration
2 mg/mL
Dilution
WB: 1:500 ;IF-Cell: 1:500 ;IHC-P: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 26 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
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