C10orf58 Mouse Monoclonal Antibody [7-B7]
FAM213A, also known as PAMM (peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) or C10orf58, is a 229 amino acid cytoplasmic protein that belongs to the peroxiredoxin-like FAM213 family and FAM213A subfamily. FAM213A involved in redox regulation of the cell. Acts as an antioxidant. Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation. May affect bone resorption and help to maintain bone mass. Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
C10orf58 antibody CJ058_HUMAN antibody UPF0765 protein C10orf58 antibody
Abbreviation
Protein PAMM, FAM213A, C10orf58, PAMM, PRO2290, PSEC0139, UNQ611/PRO1198
Swiss Prot
Q9BRX8 Human
Cellular Locus
Cytoplasm, Secreted.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within Human C10orf58 aa 1-229 / 229.
Isotype
IgG2a
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell
Positive Control
Recombinant protein, human skin tissue lysate, HepG2, HUVEC, PC-3M.
Concentration
2 mg/mL
Dilution
WB: 1:500;IF-Cell: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 26 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No
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