FAM62B Mouse Monoclonal Antibody [C4-D0]
Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS).
Product Specifications
Product Name Alternative
Abbreviation
Extended synaptotagmin-2 E-Syt21 Chr2Syt,FAM62B, KIAA1228
Swiss Prot
A0FGR8 Human
Cellular Locus
Cell membrane, Endoplasmic reticulum, Membrane.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within human FAM62B aa 300-550.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Siha cell lysate, THP-1 cell lysate, human colon carcinoma tissue.
Concentration
2 mg/mL
Dilution
WB: 1:500;IHC-P: 1:50-1:200
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
102 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
CAS Number
9007-83-4
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