BTA-2

BTA-2, a benzothiazole dye, is structurally similar to thioflavin T (ThT), which exhibits an enhanced fluorescence signal when bound to amyloid fibrils. BTA-2 has distinct absorption and emission characteristics in solution and when bound to amyloid fibrils, which makes it can used for identifying amyloid fibrils using spectroscopy[1].

Product Specifications

CAS Number

[10205-62-6]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Amyloid-β

Type

Reference compound

Related Pathways

Neuronal Signaling

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/bta-2.html

Solubility

10 mM in DMSO

Smiles

CC1=CC=C2N=C(C3=CC=C(C=C3)N(C)C)SC2=C1

Molecular Formula

C16H16N2S

Molecular Weight

268.38

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Catherine C Kitts, et al. A spectroscopic study of 2-[4'- (dimethylamino) phenyl]-benzothiazole binding to insulin amyloid fibrils. J Fluoresc. 2010 Jul;20 (4) :881-9.