BTA-2
BTA-2, a benzothiazole dye, is structurally similar to thioflavin T (ThT), which exhibits an enhanced fluorescence signal when bound to amyloid fibrils. BTA-2 has distinct absorption and emission characteristics in solution and when bound to amyloid fibrils, which makes it can used for identifying amyloid fibrils using spectroscopy[1].
Product Specifications
CAS Number
10205-62-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bta-2.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C2N=C(C3=CC=C(C=C3)N(C)C)SC2=C1
Molecular Formula
C16H16N2S
Molecular Weight
268.38
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Catherine C Kitts, et al. A spectroscopic study of 2-[4'- (dimethylamino) phenyl]-benzothiazole binding to insulin amyloid fibrils. J Fluoresc. 2010 Jul;20 (4) :881-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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