CD127 Recombinant Rabbit Monoclonal Antibody [JE37-10]
The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V (D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
IL7R
Swiss Prot
P16871 Human, P16872 Mouse
Cellular Locus
Cell membrane; Secreted.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Recombinant protein within Human CD127 aa 340-439 / 459.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
K562 cell lysates, ID8 cell lysate, SiHa, human tonsil tissue, K-562.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IF-Cell: 1:50 ;IHC-P: 1:200 ;FC: 1:500-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 52 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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