TMEM16A Recombinant Rabbit Monoclonal Antibody [PO00-27]
Anoctamin-1 (ANO1) also known as Transmembrane member 16A (TMEM16A) is a protein that, in humans, is encoded by the ANO1 gene. Anoctamin-1 is a voltage-gated calcium-activated anion channel, which acts as a chloride channel and a bicarbonate channel. additionally Anoctamin-1 is apical iodide channel. It is expressed in smooth muscle, epithelial cells, vomeronasal neurons, olfactory sustentacular cells, and is highly expressed in interstitial cells of Cajal (ICC) throughout the gastrointestinal tract. ANO1 is a transmembrane protein that functions as a calcium-activated chloride channel. Ca2+, Sr2+, and Ba2+ activate the channel.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
ANO1, DOG1, ORAOV2, TAOS2, TMEM16A
Swiss Prot
Q5XXA6 Human
Cellular Locus
Cytoplasm, Cell membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human TMEM16A aa 400-500.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
IHC-P
Positive Control
Human gastrointestinal stromal tumor tissue, human gallbladder tissue, human breast tissue.
Concentration
1 mg/mL
Dilution
IHC-P: 1:1,000-1:1,500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 114 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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