PIN4 Recombinant Rabbit Monoclonal Antibody [JE64-05]
This gene encodes a member of the parvulin subfamily of the peptidyl-prolyl cis/trans isomerase protein family. The encoded protein catalyzes the isomerization of peptidylprolyl bonds, and may play a role in the cell cycle, chromatin remodeling, and/or ribosome biogenesis. The encoded protein may play an additional role in the mitochondria. This antibody recognizes Prostate Intraepithelial Neoplasia (PIN) in the tissues stained by immunohistochemical techniques. A cocktail of thesethree antibodies might allow simultaneous demonstration of P504S, HMWCK and p63 using a single immunostain. The combination of P504S +HMW CK + p63 (PIN4 Cocktail) may be extremely useful for studying prostatic intraepithelial neoplasia, especially in difficult cases and in cases with limited tissue.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
PIN4
Swiss Prot
Q9Y237 Human, Q9CWW6 Mouse,
Cellular Locus
Nucleolus, Cytoplasm, spindle; Mitochondrion, Mitochondrion matrix.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within human PIN4 aa 82-131/131.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
293T cell lysates, rat large intestine tissue, human testis tissue, human colon carcinoma tissue, mouse esophagus tissue, mouse stomach tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 14 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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