IQGAP2 Recombinant Rabbit Monoclonal Antibody [JE64-93]
Ras GTPase-activating-like protein IQGAP2 is an enzyme that in humans is encoded by the IQGAP2 gene. This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants. IQGAP2 has been shown to interact with CDC42 and RAC1.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
IQGAP2
Swiss Prot
Q13576 Human
Cellular Locus
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human IQGAP2 aa 1,301-1,500/1,575.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Human placenta tissue lysates, human liver tissue lysate, Jurkat cell lysate, human gallbladder tissue, human prostate tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:5,000 ;IHC-P: 1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 181 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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