Septin 8 Recombinant Rabbit Monoclonal Antibody [JE64-99]
This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. They are involved in the organization of submembranous structures, in neuronal polarity, and in vesicle trafficking.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
KIAA0202 antibody OTTHUMP00000211755 antibody SEP 2 antibody SEP2 antibody SEPT 8 antibody SEPT8 antibody Septin8 antibody
Abbreviation
SEPTIN8
Swiss Prot
Q92599 Human, Q8CHH9 Mouse, B0BNF1 Rat
Cellular Locus
Cytoskeleton, cytoplasm, synapse, axon, synaptic vesicle membrane, presynapse.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within human Septin 8 aa 41-90/483.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
K562 cell lysate, LO2 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysates, rat cerebellum tissue, mouse hippocampus tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:400
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 56 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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