S-Trityl-L-cysteine
S-Trityl-L-cysteine (NSC 83265) is a selective and allosteric kinesin Eg5 inhibitor with an IC50 of 1 μM for the inhibition of basal ATPase activity and 140 nM for the microtubule-activated ATPase activity. S-Trityl-L-cysteine has antitumor activities[1][2].
Product Specifications
CAS Number
2799-07-7
Product Name Alternative
NSC 83265; S-Tritylcysteine; 3-Tritylthio-L-alanine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Kinesin
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-trityl-l-cysteine.html
Purity
99.53
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
N[C@@H](CSC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C(O)=O
Molecular Formula
C22H21NO2S
Molecular Weight
363.47
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Kinesin-5/Eg5/KSP
Available Sizes
Frequently Asked Questions
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