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IQGAP2 Recombinant Rabbit Monoclonal Antibody [JE64-54]

This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants.

Product Specifications

Product Name Alternative

IQ motif containing GTPase activating protein 2 antibody IQGA2_HUMAN antibody Iqgap2 antibody Ras GTPase activating-like protein antibody Ras GTPase-activating-like protein IQGAP2 antibody

Abbreviation

IQGAP2

Swiss Prot

Q13576 Human

Cellular Locus

Actin cytoskeleton, microtubule, cytosol, extracellular exosome, plasma membrane, cell surface, cytoplasm, filopodium, lamellipodium, microvillus, secretory granule membrane

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within human IQGAP2 aa 1,301-1,500/1,575.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

Human placenta tissue lysates, human gallbladder tissue, human prostate tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IHC-P: 1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 181 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

CAS Number

9000-83-3

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