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HNF-4-alpha Recombinant Rabbit Monoclonal Antibody [JE63-17]

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

FLJ39654 antibody FRTS4 antibody Hepatic nuclear factor 4 alpha antibody Hepatocyte nuclear factor 4 alpha antibody Hepatocyte nuclear factor 4 antibody Hepatocyte nuclear factor 4-alpha antibody HNF 4 alpha antibody HNF 4 antibody HNF-4-alpha antibody HNF4 antibody HNF4A antibody HNF4A_HUMAN antibody HNF4a7 antibody HNF4a8 antibody HNF4a9 antibody Hnf4alpha antibody HNF4alpha10/11/12 antibody MODY 1 antibody MODY antibody MODY1 antibody NR2A1 antibody NR2A21 antibody Nuclear receptor subfamily 2 group A member 1 antibody OTTHUMP00000031060 antibody OTTHUMP00000031062 antibody TCF 14 antibody TCF antibody TCF-14 antibody TCF14 antibody Tcf4 antibody Transcription factor 14, hepatic nuclear factor antibody Transcription factor 14 antibody Transcription factor HNF 4 antibody Transcription factor HNF-4 antibody Transcription factor HNF4 antibody

Abbreviation

HNF4A

Swiss Prot

P41235 Human, P49698 Mouse, P22449 Rat

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within mouse HNF-4-alpha aa 1-250/474.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, mIHC, IF-Tissue

Positive Control

HepG2 cell lysates, mouse liver tissue lysate, rat liver tissue lysate, human liver tissue, mouse liver tissue, rat colon tissue, human colon tissue, mouse colon tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IHC-P: 1:400 ;mIHC: 1:2,000-1:5,000 ;IF-Tissue: 1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 53 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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