HNF-4-alpha Recombinant Rabbit Monoclonal Antibody [JE63-17]
The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
HNF4A
Swiss Prot
P41235 Human, P49698 Mouse, P22449 Rat
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within mouse HNF-4-alpha aa 1-250/474.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, mIHC, IF-Tissue
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:400 ;mIHC: 1:2,000-1:5,000 ;IF-Tissue: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 53 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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