CLIP170 Recombinant Rabbit Monoclonal Antibody [JE63-82]
Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking. The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
CLIP1
Swiss Prot
P30622 Human
Cellular Locus
Cytoskeleton, cytoplasm, cytoplasmic vesicle membrane, ruffle.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human CLIP170 aa 1,389-1,438/1,438.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Hela cell lysate, HepG2 cell lysate, MCF-7 cell lysate, HUVEC cell lysate, JAR cell lysate, human skin tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500;IF-Cell: 1:50;IHC-P: 1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 162 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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