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iFluor™ 488 Conjugated BRG1 Recombinant Rabbit Monoclonal Antibody [SN20-03]

The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2α) and Brg-1 (also designated SNF2β) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

ATP dependent helicase SMARCA4 antibody ATP-dependent helicase SMARCA4 antibody BAF 190 antibody BAF190 antibody BAF190A antibody Brahma protein like 1 antibody BRG1 antibody BRG1 associated factor 190A antibody BRG1 protein antibody BRG1-associated factor 190A antibody BRM/SWI2 related gene 1 antibody Global transcription activator homologous sequence antibody global transcription activator snf2l4 antibody Homeotic gene regulator antibody hSNF2b antibody Mitotic growth and transcription activator antibody MRD16 antibody Nuclear protein GRB1 antibody Protein brahma homolog 1 antibody Protein BRG-1 antibody Protein BRG1 antibody RTPS2 antibody SMARC A4 antibody SMARCA4 antibody SMCA4_HUMAN antibody SNF2 antibody SNF2 beta antibody SNF2 like 4 antibody SNF2-beta antibody SNF2B antibody SNF2L4 antibody SNF2LB antibody Sucrose nonfermenting like 4 antibody SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 4 antibody SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 antibody SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4 antibody SWI2 antibody Transcription activator BRG1 antibody

Abbreviation

BAF190A, SMARCA4

Swiss Prot

P51532 Human, Q3TKT4 Mouse, Q8K1P7 Rat

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within human BRG1 aa 240-280.

Isotype

IgG

Conjugation

iFluor™ 488

Type

Recombinant Rabbit monoclonal Antibody

Applications

IF-Tissue

Positive Control

Rat brain tissue.

Concentration

1 mg/mL

Dilution

IF-Tissue: 1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.

Molecular Weight

Predicted band size: 185 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

Frequently Asked Questions

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