iFluor™ 488 Conjugated Calretinin Recombinant Rabbit Monoclonal Antibody [JM12-93]
Calbindin D28K and Calretinin (also designated CR or 29 kDa Calbindin) are two closely related intracellular calcium-binding proteins belonging to the Troponin-C superfamily. Initially isolated from chick retina, Calretinin shares 58% identical residues with human Calbindin D28K. Calretinin is expressed in the brain and is particularly abundant in auditory neurons with precisely timed discharges. Neurons in the nucleus accumbens containing Calretinin all possess nuclear indentations. Calretinin-immunoreactive boutons form asymmetrical and symmetrical synaptic specializations on spines, dendrites and somata. The symmetrical synaptic specializations have medium-sized spiny neurons and contact other Calretinin-immunoreactive somata. Calretinin is widely used as a immunocytochemical marker for mesothelioma.
Product Specifications
Product Name Alternative
Abbreviation
CR, CALB2, CAB29
Swiss Prot
P22676 Human
Cellular Locus
Cytosol, dendrite, gap junction, nucleus, parallel fiber to Purkinje cell synapse, synapse, terminal bouton.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human Calretinin aa 60-100.
Isotype
IgG
Conjugation
iFluor™ 488
Type
Recombinant Rabbit monoclonal Antibody
Applications
IF-Cell, FC
Positive Control
SH-SY5Y.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:100 ;FC: 1:500-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS
Molecular Weight
Predicted band size: 32 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
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