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NMI Recombinant Rabbit Monoclonal Antibody [JE65-78]

N-myc-interactor also known as N-myc and STAT interactor is a protein that in humans is encoded by the NMI gene. NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

N myc (and STAT) interactor antibody N myc and STAT interactor antibody N myc interactor antibody

Abbreviation

NMI

Swiss Prot

Q13287 Human

Cellular Locus

Nucleus, Secreted, Cytoplasm.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within human NMI aa 1-51/307.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

THP-1 cell lysates, human small intestine tissue, Hela, SiHa.

Concentration

1 mg/mL

Dilution

WB: 1:1,000;IF-Cell: 1:50;IHC-P: 1:400;FC: 1:500-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 35 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

Frequently Asked Questions

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