NMI Recombinant Rabbit Monoclonal Antibody [JE65-78]
N-myc-interactor also known as N-myc and STAT interactor is a protein that in humans is encoded by the NMI gene. NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
N myc (and STAT) interactor antibody N myc and STAT interactor antibody N myc interactor antibody
Abbreviation
NMI
Swiss Prot
Q13287 Human
Cellular Locus
Nucleus, Secreted, Cytoplasm.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human NMI aa 1-51/307.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
THP-1 cell lysates, human small intestine tissue, Hela, SiHa.
Concentration
1 mg/mL
Dilution
WB: 1:1,000;IF-Cell: 1:50;IHC-P: 1:400;FC: 1:500-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 35 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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