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USP39 Recombinant Rabbit Monoclonal Antibody [JE61-02]

Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the precatalytic spliceosome. Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity. The U4/U6-U5 tri-snRNP complex is a building block of the precatalytic spliceosome (spliceosome B complex). Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39, plus LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

65K antibody CGI 21 antibody CGI-21 antibody FLJ33136 antibody HSPC332 antibody Inactive ubiquitin specific peptidase 39 antibody Inactive ubiquitin-specific peptidase 39 antibody MGC75069 antibody PRO2855 antibody S. CEREVISIAE, HOMOLOG OF SAD1 antibody SAD1 antibody SAD1 homolog antibody Small nuclear ribonucleoprotein 65kDa (U4/U6.U5) antibody snRNP ASSEMBLY DEFECTIVE 1 antibody SnRNP assembly defective 1 homolog antibody SNRNP65 antibody SNUT2_HUMAN antibody U4/U6.U5 tri snRNP associated 65 kDa protein antibody U4/U6.U5 tri snRNP associated protein 2 antibody U4/U6.U5 tri-snRNP-associated 65 kDa protein antibody U4/U6.U5 tri-snRNP-associated protein 2 antibody Ubiquitin specific peptidase 39 antibody Ubiquitin specific protease 39 antibody USP39 antibody

Abbreviation

USP39

Swiss Prot

Q53GS9 Human, Q3TIX9 Mouse, B2GV41 Rat

Cellular Locus

Nucleus, Spliceosome.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human USP39 aa 466-565/565.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

Hela cell lysate, 293T cell lysate, Jurkat cell lysate, mouse lung tissue lysate, human breast carcinoma tissue, human breast tissue, human colon carcinoma tissue, human esophagus tissue, human skin tissue, human spleen tissue, human thyroid tissue, human tonsil tissue, mouse colon tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 65 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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