USP24 Recombinant Rabbit Monoclonal Antibody [JE56-50]
Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron. Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes .
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
USP24
Swiss Prot
Q9UPU5 Human, B1AY13 Mouse
Cellular Locus
Cytosol, nucleoplasm, nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide within C-terminal Human USP24.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
NIH/3T3 cell lysates, HepG2, human liver carcinoma tissue, human fetal skeletal muscle tissue, mouse liver tissue, mouse small intestine tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:50-1:100;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size:294 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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