SBDS Recombinant Rabbit Monoclonal Antibody [JE57-04]
This gene encodes a highly conserved protein that plays an essential role in ribosome biogenesis. The encoded protein interacts with elongation factor-like GTPase 1 to disassociate eukaryotic initiation factor 6 from the late cytoplasmic pre-60S ribosomal subunit allowing assembly of the 80S subunit. Mutations within this gene are associated with the autosomal recessive disorder Shwachman-Bodian-Diamond syndrome. This gene has a closely linked pseudogene that is distally located.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
SBDS
Swiss Prot
Q9Y3A5 Human, P70122 Mouse
Cellular Locus
Spindle, nucleolus, nucleoplasm, cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Recombinant protein within human SBDS aa 150-250.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
293T cell lysate, HepG2 cell lysate, human thyroid tissue, human colon tissue, human placenta tissue, mouse cerebellum tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
29 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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