Erlin-2 Recombinant Rabbit Monoclonal Antibody [JE57-03]
This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
ERLIN2
Swiss Prot
O94905 Human, Q8BFZ9 Mouse
Cellular Locus
Endoplasmic reticulum membrane.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Recombinant protein within human Erlin-2 aa 50-200 (Lumenal).
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Mouse kidney tissue lysates, SKOV-3 cell lysates, human colon carcinoma tissue, human placenta tissue, mouse brain tissue, mouse kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 38 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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