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NeuN Recombinant Mouse Monoclonal Antibody [PD01-45]

Neuronal nuclei (NeuN, Fox-3, RBFOX3) is a nuclear protein expressed in most post-mitotic neurons of the central and peripheral nervous systems. NeuN is not detected in Purkinje cells, sympathetic ganglion cells, Cajal-Retzius cells, INL retinal cells, inferior olivary, and dentate nucleus neurons. This neuronal protein was originally identified by immunoreactivity with a monoclonal antibody also called NeuN. Using MS-analysis, NeuN was later identified as the Fox-3 gene product. Fox-3 contains an RNA recognition motif and functions as a splicing regulator. Fox-3 regulates alternative splicing of NumB, promoting neuronal differentiation during development.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

FLJ56884 antibody FLJ58356 antibody Fox-1 homolog C antibody fox1 homolog C antibody Fox3 antibody FOX3NeuN antibody hexaribonucleotide binding protein 3 antibody HRNBP3 antibody NEUN antibody neuronal nuclei antibody Rbfox3 antibody RFOX3_HUMAN antibody RNA binding protein fox-1 homolog 3 antibody RNA binding protein, fox 1 homolog (C. elegans) 3 antibody hide

Abbreviation

RBFOX3

Swiss Prot

A6NFN3 Human, Q8BIF2 Mouse

Cellular Locus

Cytoplasm, Nucleus

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within human NeuN aa 20-60.

Isotype

IgG1

Conjugation

Non-conjugated

Type

Recombinant Mouse monoclonal Antibody

Applications

WB, IF-Tissue, IHC-P, IHC-Fr

Positive Control

SH-SY5Y cell lysate, SHG44 cell lysate, Human brain tissue, mouse hippocampus tissue, mouse brain tissue, mouse cerebellum tissue, rat hippocampus tissue, rat brain tissue, rat cerebellum tissue, mouse cerebellum tissue lysates, mouse cerebral cortex tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Tissue: 1:50 ;IHC-P: 1:1,000 ;IHC-Fr: 1:500

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 34 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

Frequently Asked Questions

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