Histone H3 (acetyl K18) Mouse Monoclonal Antibody [A7B6]
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
Histone H3 H3K18ac
Swiss Prot
P68431 Human, P84243 Human, Q16695 Human, Q6NXT2 Human, Q71DI3 Human
Cellular Locus
Nucleus, Chromosome.
Host
Mouse
Species Reactivity
Human
Immunogen
Synthetic peptide within Human Histone H3 aa 1-50 / 136.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell
Positive Control
Hela treated with TSA cell lysate, Hela, TSA treated Hela.
Concentration
2 mg/mL
Dilution
WB: 1:2,000 ;IF-Cell: 1:200
Purity
Protein G affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 15 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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