Calpastatin Mouse Monoclonal Antibody [A6B1]
The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
CAST
Swiss Prot
P20810 Human
Cellular Locus
Cytosol, endoplasmic reticulum, cytoplasm, membrane.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within human Calpastatin aa 501-708 / 708.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
A549 cell lysate, A431 cell lysate, Hela cell lysate, SiHa cell lysate, human esophagus tissue, A549.
Concentration
2 mg/mL
Dilution
WB: 1:500;IF-Cell: 1:100;IHC-P: 1:200
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 120 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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