Angiotensin II Type 1 Receptor Mouse Monoclonal Antibody [11B3]
Selected Variant
HA600029
Size: 100 µL
The AT1 receptor mediates the major cardiovascular effects of angiotensin II. Effects include vasoconstriction, aldosterone synthesis and secretion, increased vasopressin secretion, cardiac hypertrophy, augmentation of peripheral noradrenergic activity, vascular smooth muscle cells proliferation, decreased renal blood flow, renal renin inhibition, renal tubular sodium reuptake, modulation of central sympathetic nervous system activity, cardiac contractility, central osmocontrol and extracellular matrix formation.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
Type-1 angiotensin II receptor AT1AR AT1BR Angiotensin II type-1 receptor AT1
Swiss Prot
P30556 Human, P25095 Rat, P29089 Rat
Cellular Locus
Cell membrane, Membrane.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human Angiotensin II Type 1 Receptor aa 300-350.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, FC
Positive Control
PC-12 cell lysate, A549 cell lysate, HepG2 cell lysate, HeLa cell lysate, PC-12, 293T, A549.
Concentration
2 mg/mL
Dilution
WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:100 ;FC: 1:50-1:100
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 41 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Price
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