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Angiotensin II Type 1 Receptor Mouse Monoclonal Antibody [11B3]

The AT1 receptor mediates the major cardiovascular effects of angiotensin II. Effects include vasoconstriction, aldosterone synthesis and secretion, increased vasopressin secretion, cardiac hypertrophy, augmentation of peripheral noradrenergic activity, vascular smooth muscle cells proliferation, decreased renal blood flow, renal renin inhibition, renal tubular sodium reuptake, modulation of central sympathetic nervous system activity, cardiac contractility, central osmocontrol and extracellular matrix formation.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

AG2S antibody Agtr 1 antibody Agtr1 antibody AGTR1_HUMAN antibody Agtr1a antibody AGTR1B antibody Ang II antibody Angiotensin II receptor type 1 antibody Angiotensin II type-1 receptor antibody Angiotensin receptor 1 antibody Angiotensin receptor 1B antibody AT 1B antibody AT 1r antibody AT1 antibody At1a antibody AT1AR antibody AT1B antibody AT1BR antibody AT1R antibody AT2R1 antibody AT2R1A antibody AT2R1B antibody HAT1R antibody Type 1 angiotensin II receptor antibody Type 1B angiotensin II receptor antibody Type-1 angiotensin II receptor antibody

Abbreviation

Type-1 angiotensin II receptor AT1AR AT1BR Angiotensin II type-1 receptor AT1

Swiss Prot

P30556 Human, P25095 Rat, P29089 Rat

Cellular Locus

Cell membrane, Membrane.

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within human Angiotensin II Type 1 Receptor aa 300-350.

Isotype

IgG1

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IF-Cell, FC

Positive Control

PC-12 cell lysate, A549 cell lysate, HepG2 cell lysate, HeLa cell lysate, PC-12, 293T, A549.

Concentration

2 mg/mL

Dilution

WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:100 ;FC: 1:50-1:100

Purity

Protein G affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 41 kDa.

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

Curated Selection

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